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KMID : 1036520110010020097
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Clinical Neuro-Ophthalmology
2011 Volume.1 No. 2 p.97 ~ p.103
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Inflammatory Optic Neuropathy
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Oh Sun-Young
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Abstract
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Inflammatory optic neuropathies are common in clinical practice and a wide variety of illnesses produce inflammation of the optic nerves, i.e., optic neuritis (ON). Monosymptomatic optic neuritis has important implications for the development of multiple sclerosis. In the patient presenting with monosymptomatic optic neuritis, MR imaging provides critical prognostic information concerning the development of MS. The Optic Neuritis Treatment Trial (ONTT) has provided valuable insights into both the natural history and clinical course of demyelinating ON with respect to treatment. Intravenous methylprednisolone remains a viable treatment option to slightly increase the rate of recovery and provide a degree of short-term protection against the subsequent development of MS. There are multiple causes of inflammatory optic neuritis, including infectious diseases such as syphilis and cat scratch disease, and noninfectious inflammation such as NMO (neuromyelitis optica, Devic’s disease), sarcoidosis with each possessing distinct clinical characteristics and treatment approaches.
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KEYWORD
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Optic neuritis, Multiple sclerosis (MS), Neuromyelitis optica (NMO), Management
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